This project aims to develop new software, sigViz, which researchers can use to create interactive dynamic models of cell signaling pathways that portray accurate structural details for improved communication and hypothesis generation. The tool will serve as an interface for systems biology simulators and by default contains a coarse flux network simulator that non-computational biologists can easily modify or extend. As a Cytoscape plugin, sigViz can natively output simple static and animated graphics, but to impact a broader audience the project will plug into the ubiquitous Python API (uPy) to enable users to create professional quality images and animations driven directly by the interoperating sigViz models. The sigViz app will function in a variety of popular interfaces, including web browsers, to enable researchers from any background to easily access and use the tools with no special training or hardware. To disseminate the software and to encourage a broad community to contribute and curate sigViz models, this project will extend the functionality of an existing database, WikiPathways, to integrate with sigViz and its datatypes rather than directly creating any databases or repositories from scratch.